The Relationships of Anhedonia and the Process-Reactive Dimension to Season of Birth and Infectious Disease Incidence in Schizophrenia
作者:
CHARLES WATSON,
TERESA KUCALA,
GAIL ANGULSKI,
PATRICIA VASSAR,
期刊:
The Journal of Nervous and Mental Disease
(OVID Available online 1987)
卷期:
Volume 175,
issue 1
页码: 34-40
ISSN:0022-3018
年代: 1987
出版商: OVID
数据来源: OVID
摘要:
This project was designed to test two hypotheses drawn from a new formulation explaining the exaggerated winter birthrate among hospitalized schizophrenics. The first is that the supposed exaggerated winter birthrate among process schizophrenics actually represents a reduction in spring-fall births caused by prenatal exposure to infectious diseases during the preceding winter—i.e., a high prenatal death rate in process preschizophrenic fetuses. The second is that the level of negative symptoms in survivors at risk for schizophrenia who were born after winters with high infectious disease rates is exaggerated. The findings provided some tentative support for this formulation. Compared with counterparts born after low-disease winters, schizophrenics born after winters with high disease incidences tended to show lower (more reactive) scores on a measure of the process-reaction dimension but higher anhedonia scores.
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