Left Ventricular Mass and Exercise Responses Predict Future Blood Pressure The Muscatine Study
作者:
LARRY MAHONEY,
RICHARD SCHIEKEN,
WILLIAM CLARKE,
RONALD LAUER,
期刊:
Hypertension
(OVID Available online 1988)
卷期:
Volume 12,
issue 2
页码: 206-213
ISSN:0194-911X
年代: 1988
出版商: OVID
关键词: left ventricular mass;blood pressure;echocardiography;childhood
数据来源: OVID
摘要:
Increased blood pressure and left ventricular mass are associated with increased morbidity and mortality in adults with coronary heart disease. To define the predictors of subsequent childhood blood pressure and left ventricular mass, serial echocardiograms and blood pressure responses during exercise were studied in 274 children aged 6 to IS years, whose systolic blood pressures were in the high, middle, or low range. Persistence of rank order for left ventricular mass and blood pressure, at rest and during exercise, was maintained over a mean follow-up period of 3.4 years, with correlations ranging from 0.33 to 0.44. Subsequent systolic blood pressure was best predicted from initial resting and maximal exercise systolic blood pressures and left ventricular mass. Subsequent left ventricular mass was best predicted from initial left ventricular mass and maximal exercise diastolic blood pressure, but resting systolic blood pressure did not add to this latter prediction. Since left ventricular mass relates best to exercise blood pressure and not to resting Mood pressure, left ventricular mass may provide an integrated view of the effects of blood pressure both at rest and during stress. We speculate that increased left ventricular mass in childhood may be an important predictor of subsequent hypertension and its consequences.
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