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Pure Red Cell Aplasia Following ABO Mismatched Marrow Transplantation for Chronic Lymphocytic Leukemia: Response to Antithymocyte Globulin

 

作者: BiermanPhilip J.,   WarkentinPhyllis,   HutchinsMark R.,   KlassenLynell W.,  

 

期刊: Leukemia&Lymphoma  （Taylor Available online 1993）
卷期: Volume 9, issue 1-2  

页码: 169-171

 

ISSN:1042-8194

 

年代: 1993

 

DOI:10.3109/10428199309148522

 

出版商: Taylor&Francis

 

关键词: Bone marrow transplantation;ABO mismatched marrow transplantation;red Blood cell aplasia;antithymocyte globulin;chronic lymphocytic leukemia

 

数据来源: Taylor

 

摘要:

Pure red cell aplasia was observed in a 28 year old woman following a major ABO mismatched allogeneic bone marrow transplant for chronic lymphocytic leukemia. No evidence of red Blood cell production was observed for more than one year following transplant despite the absence of high isohemagglutinin titers. Treatment with antithymocyte globulin resulted in prompt restoration of reticulocytosis. Therapy with antithymocyte globulin should be considered in these instances when red cell aplasia follows mismatched allogeneic marrow transplantation.

 

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