Craniofacial bone remodeling in growing rats fed a low-calcium and vitamin-D-deficient diet and the influence of masticatory muscle function
作者:
KiliaridisStavros,
EngströmChrister,
StoklandBirgitta Lindskog,
KatsarosChristos,
期刊:
Acta Odontologica Scandinavica
(Taylor Available online 1996)
卷期:
Volume 54,
issue 5
页码: 320-326
ISSN:0001-6357
年代: 1996
DOI:10.3109/00016359609003545
出版商: Taylor&Francis
关键词: Fluorescence;growth;hypocalcemia;microradiography
数据来源: Taylor
摘要:
Fifty-two male growing rats were randomly divided into three groups. The first group (n= 18) received a hard deficient diet, and the second (n= 18) a soft deficient diet. The control group (n= 16) was fed the normal hard diet. At the beginning and in the middle of the 28-day experimental period oxytetracycline was injected. Two representative coronal sections of the snout and the corresponding contact microradiographs were analyzed. The bone mass of die premaxillary and nasal bones seemed to be less in die two deficient diet groups than in the normal one, due to an increased endosteal bone resorption and decreased bone formation. No difference in the bone apposition rate and pattern could be seen between me deficient hard and soft diet groups, except in the dorsal part of the premaxilla, where the bone formed in the first half of the experiment was markedly more resorbed in die deficient soft diet group during die remaining period than in the deficient hard diet group. The morphology of the sutures was influenced by the altered function, since the sutural space became narrower, and premature obliterations of the intemasal suture were observed in the deficient soft diet group. In conclusion, poor bone quality was observed in the skull of rats fed a low-calcium and vitamin-D-deficient diet, with less bone mass than in normal conditions. Masticatory function was a significant factor influencing bone remodeling and sutural growth even in situations in which a metabolic bone disturbance exists.
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