Structure and Role of Langerhans’ Cells in the Human Oesophageal Epithelium
作者:
Benoît Terris,
François Potet,
期刊:
Digestion
(Karger Available online 1995)
卷期:
Volume 56,
issue 1
页码: 9-14
ISSN:0012-2823
年代: 1995
DOI:10.1159/000201295
出版商: S. Karger AG
关键词: Oesophagus;Langerhans’ cells;Dendritic cells;Immunohistochemistry;Immunologic defense;Oesophagitis;HIV infection;Gut-associated lymphoid tissue;Cytokines;Calcitonin gene-related peptides
数据来源: Karger
摘要:
Oesophageal Langerhans’ cells (LC) are bone marrow-derived dendritic cells situated suprabasally in most stratified squamous epithelia, such as the epidermis and the epithelium of oesophageal mucosa. LC function as antigen-presenting cells. Associated with relatively numerous intra-epithelial lymphocytes present in the normal state in oesophageal mucosa, they play a major role in the immunologic defense system of the oesophagus. Structure and role of LC are summarized in this review. Moreover, the implications of LC in different pathologic oesophageal reactions are discusse
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