Chapter 6: Cell and cell system responses: The delayed respiratory consequences of inhaled radionuclides in population exposed to nuclear catastrophe
作者:
Alexander G. Chuchalin,
Olga M. Grobova,
Andre L. Cherniaev,
Aleksey R. Tatarsky,
Didier Hoffshir,
Cyr Voisin,
期刊:
STEM CELLS
(WILEY Available online 1995)
卷期:
Volume 13,
issue S1
页码: 276-282
ISSN:1066-5099
年代: 1995
DOI:10.1002/stem.5530130734
出版商: John Wiley&Sons, Ltd.
关键词: Chernobyl;Exposed population;Radionuclides;Lung;Bronchoalveolar lavage;x‐ray spectrometry
数据来源: WILEY
摘要:
AbstractCytological analysis of bronchoalveolar lavage (BAL) and x‐ray energy dispersive spectrometry of intercellular compounds were evaluated in 19 workers (“liquidators”) commissioned to clean and contain the nuclear waste after the Chernobyl catastrophe in comparison with ten control subjects. Results showed a significant increase of neutrophils, small monocyte‐like alveolar macrophages (AM) and AM with large black cytoplasmic inclusions. In addition, such mineral elements as Zr, Ce, Pr, Sm, Pa, PU and Cs were detected in AM phagosomes in liquidators. These elements were reported as markers of Chernobyl‐type nuclear fuel. It is recognized that BAL gives access to particulate matter present in lung parenchyma. Thus, spectrometric analysis of AM inclusions can provide reliable information about the exposure to inhaled radionuclides seven years after the ca
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