Acetylcholine supersensitivity in the rat heart produced by neonatal sympathectomy
作者:
Kunio Ishii,
Norie Ishii,
Koki Shigenobu,
Yutaka Kasuya,
期刊:
Canadian Journal of Physiology and Pharmacology
(NRC Available online 1985)
卷期:
Volume 63,
issue 7
页码: 898-899
ISSN:0008-4212
年代: 1985
DOI:10.1139/y85-147
出版商: NRC Research Press
数据来源: NRC
摘要:
Effects of neonatal sympathectomy with antiserum to nerve growth factor or 6-hydroxydopamine on the acetylcholine sensitivity of the rat left atria were investigated. Sensitivities to acetylcholine of atria from immunologically and chemically sympathectomized rats were much higher than that of control at 4 weeks of age. These results suggest possible involvement of the sympathetic nervous system in regulation of cardiac cholinergic sensitivity.
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