HLA Typing of a Family with Systemic Lupus Erythematosus
作者:
KagawaHideo,
OzakiYoshio,
UehiraKazutaka,
NomuraShosaku,
MatsuzakiTatsunoki,
IshidaTomoko,
FukuharaShirou,
期刊:
Autoimmunity
(Taylor Available online 1996)
卷期:
Volume 24,
issue 4
页码: 265-266
ISSN:0891-6934
年代: 1996
DOI:10.3109/08916939608994719
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Although systemic lupus erythematosus (SLE) is a representative collagen disease, the etiology remains unclear. However, both genetic and environmental factors seem to be involved. Based on serological studies, associations between certain human leukocyte antigens and many autoimmune diseases have long been suggested. Regarding the genetic aspects of SLE, the HLA haplotype is regarded as a potentially important factor, although its role remains controversial. Recently, we examined three family members who had SLE with an identical HLA haplotype.
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