Pharmacology of serotonin neuronal systems
作者:
C. A. Fontes Ribeiro,
期刊:
Human Psychopharmacology: Clinical and Experimental
(WILEY Available online 1991)
卷期:
Volume 6,
issue S1
页码: 37-51
ISSN:0885-6222
年代: 1991
DOI:10.1002/hup.470060508
出版商: John Wiley&Sons, Ltd.
关键词: synthesis;release;inactivation;5‐HT receptors;interactions
数据来源: WILEY
摘要:
AbstractThis review concerns the pharmacology of the serotonergic systems in the CNS. After the description of the anatomy of the serotonergic system the synthesis, release and inactivation of the neurotransmitter 5‐HT is delineated. From the different serotonergic receptors (5‐HT1A, 5‐HT1B, 5‐HT1C, 5‐HT1D, 5‐HT2and 5‐HT3) the current status with regard to available ligands, second messenger systems and physiological roles has been outlined. The last part of the review extends the relationship between the 5‐HT and other neurotransmitter systems in the CNS (e.g. dopamine, noradrenaline, substance P, glutamate, acetylcholine a
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