Hypopituitarism Stabilizes the Renal and Retinal Complications of Diabetes mellitus
作者:
Mark Plumb,
Karl Nath,
Elizabeth R. Seaquist,
期刊:
American Journal of Nephrology
(Karger Available online 1992)
卷期:
Volume 12,
issue 4
页码: 265-267
ISSN:0250-8095
年代: 1992
DOI:10.1159/000168456
出版商: S. Karger AG
关键词: Diabetic nephropathy;Diabetic retinopathy;Hypopituitarism
数据来源: Karger
摘要:
In 1953, Poulsen described the remarkable case of a woman with type I diabetes mellitus who experienced resolution of her retinopathy following postpartum pituitary necrosis [1]. Since that time, many investigators have pursued the hypothesis that anterior pituitary hormones, particularly growth hormone, play a role in the pathogenesis of the microvascular complications of diabetes mellitus. While most observers have demonstrated the importance of growth hormone in the initiation and progression of diabetic retinopathy [2, 3], the role of growth hormone in the development of diabetic nephropathy has been more difficult to document. In this case report, we describe a woman with long-standing type I diabetes mellitus complicated by retinopathy and nephropathy whose complications stabilized as she developed growth hormone deficiency.
点击下载:
PDF
(484KB)
返 回