Reproductive Function in Epilepsy
作者:
Joyce A. Cramer,
Ervin E. Jones,
期刊:
Epilepsia
(WILEY Available online 1991)
卷期:
Volume 32,
issue 1
页码: 19-26
ISSN:0013-9580
年代: 1991
DOI:10.1111/j.1528-1157.1991.tb05887.x
出版商: Blackwell Publishing Ltd
关键词: Epilepsy;Anticonvulsants;Drug‐induced abnormalities;Hormones;Reproduction;Hypothalmus;Pituitary;Menstrual cycle
数据来源: WILEY
摘要:
Summary:: The hypothalamic‐pituitary‐gonadal axis is a complex system within which both positive and negative feedback occur among its elements and higher brain systems. The occurrence of seizures and changes in the secretion of pituitary hormones can affect the feedback loop. Both seizures and antiepileptic drugs can affect the hypothalamic‐pituitary‐gonadal axis of males and females and cause changes in hormones and sexuality. Reproductive dysfunction has a social impact because of reduced fertility. Once conception occurs, live birth rates are not diminished. Prospective studies of men and women with epilepsy are
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