首页   按字顺浏览 期刊浏览 卷期浏览 Immunopathology of Alkaline Phosphatase Isozymes in Seminoma
Immunopathology of Alkaline Phosphatase Isozymes in Seminoma

 

作者: Hajime Yamamoto,   Tadao Uchibayashi,   Kiyoshi Koshida,   Kazuyuki Hirano,   Haruo Hisazumi,  

 

期刊: Urologia Internationalis  （Karger Available online 1993）
卷期: Volume 50, issue 1  

页码: 33-35

 

ISSN:0042-1138

 

年代: 1993

 

DOI:10.1159/000282444

 

出版商: S. Karger AG

 

关键词: Testicular tumors;Seminoma;Placental alkaline phosphatase-like enzyme;Liver alkaline phosphatase;Intestinal alkaline phosphatase

 

数据来源: Karger

 

摘要:

An immunohistopathological study using monoclonal antibodies for alkaline phosphatases demonstrated placental alkaline phosphatase (PLAP)-like substance in the tumor cells of 11 pure seminomas, 1 seminoma with embryonal carcinoma and 1 seminoma metastasis. Liver alkaline phosphatase (LAP) could also be demonstrated in all seminomas but a third intestinal alkaline phosphatase (IAP) was not demonstrable in any tumor. The PLAP-like substance and LAP had considerable enzyme activities. This provides two tumor markers of seminomas detectable in histopathological specimens.

 

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