Representation of nociceptive stimuli in primary sensory cortex
作者:
Howard Berman,
Karl Kim,
Ardesheer Talati,
Joy Hirsch,
期刊:
NeuroReport
(OVID Available online 1998)
卷期:
Volume 9,
issue 18
页码: 4179-4187
ISSN:0959-4965
年代: 1998
出版商: OVID
关键词: Functional magnetic resonance imaging (fMRI);Nociception;Somatosensory cortex (SI);Somatotopy
数据来源: OVID
摘要:
USING fMRI, we observed cortical activity associated with nociceptive hot and cold sensations applied to hand and foot that are not spatially restricted to the corresponding regions of the primary somatosensory cortex (SI). Hot (55–57°C) and cold (0–2°C) tactile stimuli were applied separately to the right hand and foot of eight right-handed subjects. Although somatotopic mapping of hand and foot was observed as expected based on the Penfield homunculus, activations associated with hot during both hand and foot stimulation and subsequently, cold, activated regions unique to each thermal modality irrespective of the body part. This distributed system for thermal information is present at both nociceptive and more neutral thermal intensities (i.e. warm and cool sensations) indicating the presence of distributed sensory processing associated with thermal-related sensations in human primary sensorimotor cortex.
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