Determination of Aspirin, Salicylic Acid, Salicyluric Acid, and Gentisic Acid in Human Plasma and Urine by High Pressure Liquid Chromatography
作者:
EdwinN. Amick,
WilliamD. Mason,
期刊:
Analytical Letters
(Taylor Available online 1979)
卷期:
Volume 12,
issue 6
页码: 629-640
ISSN:0003-2719
年代: 1979
DOI:10.1080/00032717908055714
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A method has been developed to simultaneously determine aspirin, salicylic acid, salicyluric acid, and gentisic acid concentrations in human plasma and urine. An extraction and dry-down step prepare the sample for resolution by reverse-phase high pressure liquid chromatography. The column effluent is monitored by both ultraviolet absorbance and fluorescence to optimize sensitivity and specificity for the compounds of interest.
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