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Determination of Dihydro-5,6-Dehydrokawain in Rat Plasma by HPLC and its Pharmacokinetics Application

 

作者: T.H. Tsai,   S.Y. Hsu,   C.J. Chou,   T.R. Tsai,   C.F. Chen,  

 

期刊: Journal of Liquid Chromatography & Related Technologies  （Taylor Available online 1996）
卷期: Volume 19, issue 7  

页码: 1127-1137

 

ISSN:1082-6076

 

年代: 1996

 

DOI:10.1080/10826079608006307

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

A simple high performance liquid chromatographic method was developed to study the pharmacokinetics of dihydro-5,6-dehydrokawain (DDK) in the rat plasma. After addition of an internal standard (osthole), plasma was deproteinized by acetonitrile for sample clean-up. The drugs were separated on a reverse phase column and detected by UV detection at a wavelength 281 nm.

 

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