Isolated leukemic choroidal relapse in a child with acute lymphoblastic leukemia one year off therapy, diagnosed through transvitreal retino‐choroidal biopsy
作者:
Kjeld Schmiegelow,
Erik Scherfig,
Jan Ulrik Prause,
Ove Aksel Jensen,
期刊:
Acta Ophthalmologica
(WILEY Available online 1988)
卷期:
Volume 66,
issue 1
页码: 33-37
ISSN:1755-375X
年代: 1988
DOI:10.1111/j.1755-3768.1988.tb08530.x
出版商: Blackwell Publishing Ltd
关键词: choroidal leukemic relapse;childhood acute lymphoblastic leukemia;choroidal biopsy;transvitreal biopsy;vitrectomy
数据来源: WILEY
摘要:
Abstract.A serous retinal detachment and choroidal hemorrhagic infiltration developed in a 17‐year‐old girl with acute lymphoblastic leukemia one year after cessation of therapy without concurrent bone marrow (BM) or central nervous system relapse. A choroidal biopsy through a sclerotomy with simultaneous release of subretinal fluid revealed no malignant cells. Accordingly, she was treated with prednisone, topical corticosteroid and atropine with normalisation of vision and clinical findings. Five months later the retinal detachment and choroidal infiltration recurred. In order to re‐attach the retina once more and obtain a representative choroidal biopsy, a pars plana vitrectomy followed by a retinotomy with removal of subretinal tissue was done revealing leukemic infiltration of the choroid. Simultaneously a BM relapse was diag
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