A new method for predicting the impact sensitivity of explosive molecules is presented. This method makes use of a network of formal neurons. The experiment uses 124 molecules belonging to different families. The molecular descriptors taken into account are the molecule's oxygen balance and the enumeration of certain groups. The results obtained are satisfactory: 80% of the molecules are correctly classed on a scale of four sensitivities. Comparison with a multivariate linear regression analysis gives a slight advantage to the neural network method.