Chromatid lesions and chromatid core morphology
作者:
K.L. Satya-Prakash,
T.C. Hsu,
S. Pathak,
期刊:
Cytogenetic and Genome Research
(Karger Available online 1981)
卷期:
Volume 30,
issue 4
页码: 248-252
ISSN:1424-8581
年代: 1981
DOI:10.1159/000131616
出版商: S. Karger AG
数据来源: Karger
摘要:
A silver-staining technique revealed the core morphology of metaphase chromosomes of irradiated CHO cells with chromatid lesions (breaks, gaps). These cells were photographed before and after silver staining. As a rule, the core was not continuous in chromatid gaps, suggesting that the chromatid is broken in many so-called gaps. Ten cytogeneticists who were asked to classify chromatid gaps and breaks from photographs of chromosome lesions before silver core staining agreed in only 19 of 53 cases.
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