The Darapsky method has been successfully applied to the synthesis of aminoacids from substituted cyanoacetic esters, RCH (CN)COOC2H5. R=CH3CH (CH2)4CH3, CH3CH(CH2)5CH3, CH3(CH2)11, HOCH2CH2,o-ClC6H4CH2,p-CH3C6H4O(CH2)2,p-CH3C6H4O(CH2)3,p-C2H5C6H4O(CH2)2,p-C2H5C6H4O(CH2)3,p-ClC6H4O(CH2)2,p-ClC6H4O(CH2)3,p-BrC6H4O(CH2)3. The esters were prepared by condensation of cyanoacetic ester with suitable bromides. When treated with hydrazine hydrate, they gave rise to hydrazides, which were identified by their anisal derivatives. Azides were obtained by the action of nitrous acid on hydrazides at low temperature and were transformed by heating with alcohol into carbethoxyaminonitriles. Finally, the latter by hydrolysis yielded the following amino acids:dl-α-amino-β-methylcaprylic acid,dl-α-amino-β-methylpelargonic acid,dl-α-aminomyristic acid,dl-α-amino-γ-hydroxybutyric acid,dl-α-amino-γ-p-methylphenoxybutyric acid,dl-α-amino-δ-p-methylphenoxyvaleric acid,dl-α-amino-γ-p-ethylphenoxybutyric acid,dl-α-amino-δ-p-ethylphenoxyvaleric acid,dl-α-amino-γ-p-chlorophenoxybutyric acid,dl-α-amino-δ-p-chlorophenoxyvaleric acid, anddl-α-amino-δ-p-bromophenoxyvaleric acid.