The histones/DNA ratio has been calculated in the 2C nuclei from the primary root meristems of young and old caryopses ofTriticum durum.In a first experiment young and old caryopses taken from different crops were considered in one and the same trial, at the same time. In a second experiment young and old caryopses taken from the very same crop were considered in different trials at different times. In both cases 2C meristematic nuclei of old caryopses show a higher amount of DNA bound histones and smaller average nuclear area as compared to 2C meristematic nuclei of young caryopses. The possible significance of this variations in histones/DNA ratio and in nuclear areas detected in the study is discussed.