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DIRECT RESOLUTION OF ISAMOLTANE (CGP 361A) AND ENCIPRAZINE (WY 48624) ENANTIOMERS, USING CHIRAL HIGH PERFORMANCE LIQUID CHROMATOGRAPHY

 

作者: R. Ferretti,   B. Gallinella,   F. La Torre,   L. Zanitti,  

 

期刊: Journal of Liquid Chromatography & Related Technologies  （Taylor Available online 1999）
卷期: Volume 22, issue 12  

页码: 1877-1892

 

ISSN:1082-6076

 

年代: 1999

 

DOI:10.1081/JLC-100101773

 

出版商: Taylor & Francis Group

 

数据来源: Taylor

 

摘要:

A chiral high performance liquid chromatography method was developed for the resolution of the enantiomers of two new β-aminoalcohols, isamoltane and enciprazine. The separation of the enantiomers was accomplished, without any derivatization, on a chiral column containing 3,5-dimethylphenylcarbamate of cellulose (Chiralcel OD) as chiral selector.

 

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