&NA;This article deals with clinical application of the pharmacologic inhibition of gastrointestinal secretions in the management of cecal fistulas. The use of inhibitors of digestive secretions is described. The use of intravenous hyperalimentation as a depressant of intestinal secretions in the treatment of gastrointestinal fistulas is discussed. It allows “immobilization” of the gastrointestinal tract and, at the same time, supplies high caloric intake. First mentioned in 1948 by Thomas and Ross, it was more scientifically applied in the management of fistulas by Dudricket al.,7in 1970.Sterile preparation of the hyperalimentation regimen is presented. Two illustrative cases are described. It is concluded that the IVH should be used in the management of inflammatory processes of the gastrointestinal tract and in the management of fistulas complicating these processes.