The Wisconsin Card Sorting Test (WCST) Performance in Normal Subjects: A Twin Study
作者:
Arturo Campana,
Fabio Macciardi,
Orsola Gambini,
Silvio Scarone,
期刊:
Neuropsychobiology
(Karger Available online 1996)
卷期:
Volume 34,
issue 1
页码: 14-17
ISSN:0302-282X
年代: 1996
DOI:10.1159/000119284
出版商: S. Karger AG
关键词: Wisconsin Card Sorting Test;Prefrontal cortex;Neuropsychology;Twin studies;Schizophrenia
数据来源: Karger
摘要:
The aim of this study was to evaluate the WCST, a task linked to the frontal (prefrontal) cortex, in normal twins to detect an inherited component of frontal lobe function. The WCST scores of 15 monozygotic (MZ) twin pairs, 9 dizygotic (DZ) twin pairs, and 15 unrelated control pairs were used to compute genetic estimates. No significant differences were detected between MZ, DZ and control groups intrapair correlation coefficients. No significant herita-bility estimates different by zero were computed. The frontal lobe function measured by WCST performance in normal twins does not seem to have a high degree of genetic component, and larger samples of twins are required to detect low genetic effects. The possible implications of such results about the genetic predisposition of frontal deficit in schizophrenia have been discussed.
点击下载:
PDF
(799KB)
返 回