Metastatic Crohn's Disease: A Case Report
作者:
Rebecca E. Cummins,
Diane Mullins,
Linda J. Smith,
Michael J. Ford,
期刊:
Pediatric Dermatology
(WILEY Available online 1996)
卷期:
Volume 13,
issue 1
页码: 25-28
ISSN:0736-8046
年代: 1996
DOI:10.1111/j.1525-1470.1996.tb01182.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Abstract:Metastatic Crohn's disease (MCD) is a rare extraintestinal manifestation of Crohn's disease characterized by the histologic finding of granulomatous dermatitis at a site noncontiguous to the gastrointestinal tract. An adolescent had MCD of the face that was initially mistaken for severe, treatment‐resistant acne. Histopathologic and microbiologic evaluation, combined with clinical examination and response to therapy, ultimately led to the correct diagnosis.Mycobacterium paratuberculosisis a suspected cause of Crohn's disease. Polymerase chain reaction was used to detect genomic DNA specific for the organism in biopsy specimens from the patient's cutaneous lesions. This study failed to demonstrateM. paratuberculosisin the specimen
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