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Synthesis of deuterium labelled trifluoperazine

 

作者: H. U. Shetty,   E. M. Hawes,   K. K. Midha,  

 

期刊: Journal of Labelled Compounds and Radiopharmaceuticals  （WILEY Available online 1981）
卷期: Volume 18, issue 11  

页码: 1633-1640

 

ISSN:0362-4803

 

年代: 1981

 

DOI:10.1002/jlcr.2580181109

 

出版商: John Wiley&Sons, Ltd.

 

关键词: Trifluoperazine;deuterium labelling

 

数据来源: WILEY

 

摘要:

AbstractProcedures for the preparation of trifluoperazine with two, four and six deuterium atoms are described. Deuterium was introduced in the propylpiperazine side chain by treatment of the appropriate amide with lithium aluminium deuteride. The isotopic purity of the products was greater than 96.2%.

 

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