Medullary carcinoma of the thyroid: A cytological, immunocytochemical, and ultrastructural study
作者:
Shika Bose,
Kusum Kapila,
Kusum Verma,
期刊:
Diagnostic Cytopathology
(WILEY Available online 1992)
卷期:
Volume 8,
issue 1
页码: 28-32
ISSN:8755-1039
年代: 1992
DOI:10.1002/dc.2840080107
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Calcitonin;Medullary carcinoma;Immunocytology
数据来源: WILEY
摘要:
AbstractThe cytomorphological features of 38 cases of medullary carcinoma of the thyroid on FNAC were studied. These cases were retrieved from the files of the cytopathology laboratory. In addition, staining for calcitonin (19 cases), thyroglobulin (5 cases), neurone specific enolase (7 cases), and carcinoembryonic antigen (8 cases) was done. Electron microscopy was done in two cases. On morphology, the presence of amyloid together with cytoplasmic granules was found to be diagnostic. The plasmacytoid cell type and the mixed cell populations were most commonly observed. Pseudonuclear inclusions were seen in 58% of cases. Calcitonin was present in 74% of cases. NSE was noncontributory, whereas CEA was positive in one of the calcitonin negative cases.
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