In general, physical processes are usually nonlinear and control system design based on the linearization technique cannot control the process well for a wide range of operation. Use of the variable transformation method may not always solve the problem. In this paper, a fuzzy adaptive controller is proposed to control the nonlinear process. The CSTR control problem has also been considered. The results are compared with the method of nonlinear model predictive control (NMPC) with constrained and unconstrained control variables. A fuzzy model-following control system scheme is also proposed. The results show that the proposed controller is a feasible control structure for a nonlinear or parameter-variations process control.