The FT-IR (from 50 to -180°C) and the FT-Raman spectra at 25°C of glutarimide in in the solid state are investigated. The data are compared with recent results of Bienko et al.(J.Phys.Chem.A 101, 7834 (1997) on glutarimide isolated in a low-temperature argon matrix. The vibrational changes induced by hydrogen bond formation in the crystalline state are discussed. The v(NH…O) vibration is observed at 3189 cm−1at 25°C and at 3163 cm−1at -180°C. These values correspond to a contraction of the N…O distance of 0.022 Å.