Reducing noise damage by using a mid‐frequency sound conditioning stimulus
作者:
Barbara Canlon,
Anette Fransson,
期刊:
NeuroReport
(OVID Available online 1998)
卷期:
Volume 9,
issue 2
页码: 269-270
ISSN:0959-4965
年代: 1998
出版商: OVID
关键词: Auditory;Auditory brain stem response;Cochlea;Distortion product emissions;Guinea pig;Noise;Protection;Sound conditioning
数据来源: OVID
摘要:
SOUND conditioning guinea pigs to a 6.3 kHz tone at 78 dB SPL for either 13 or 24 days provides significant physiological (auditory brain stem responses, ABR; and distortion product otoacoustic emissions, DPOAE) and morphological (cochleograms) protection against a subsequent traumatic exposure (6.3 kHz, 100 dB SPL for 24 h) delivered 2 h after sound conditioning. Threshold shifts (ABR, DPOAE) were significantly reduced and the degree of hair cell loss was minimal. When a 1 week pause was given between the end of the sound conditioning and the traumatic exposure, protection was still observed, but to a lesser degree. These findings demonstrate that mid-frequency sound conditioning protects against noise trauma and that the protective effect is maintained for at least 1 week.
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