Inhibin‐A Levels and Severity of Hypertensive Disorders Due to Pregnancy
作者:
Gerda Zeeman,
James Alexander,
Donald McIntire,
William Byrd,
Kenneth Leveno,
期刊:
Obstetrics & Gynecology
(OVID Available online 2002)
卷期:
Volume 100,
issue 1
页码: 140-144
ISSN:0029-7844
年代: 2002
出版商: OVID
数据来源: OVID
摘要:
OBJECTIVETo evaluate the use of 3rd trimester inhibin-A levels as an adjunct to assess severity of hypertensive disorders due to pregnancy in women evaluated for preeclampsia.METHODSSerum inhibin-A concentration was measured in a consecutive series of women evaluated for preeclampsia in the third trimester of pregnancy.RESULTSInhibin-A levels were significantly associated with the severity of proteinuric hypertensive disease due to pregnancy. Women with gestational hypertension or those with chronic hypertension without superimposed preeclampsia had levels comparable with normotensive women. The sensitivity to detect proteinuric hypertension was 16%.CONCLUSIONAlthough inhibin-A levels rise with increasing severity of disease, due to considerable overlap of normal and abnormal serum levels in women with and without preeclampsia, inhibin-A is not a useful adjunct for the classification of hypertensive disorders due to pregnancy.
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