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Ophthalmic Features of Fourteen Cases of Goodpasture’s Syndrome

 

作者: Peter A. Rowe,   David C. Mansfield,   Gordon N. Dutton,  

 

期刊: Nephron  (Karger Available online 1994)
卷期: Volume 68, issue 1  

页码: 52-56

 

ISSN:1660-8151

 

年代: 1994

 

DOI:10.1159/000188087

 

出版商: S. Karger AG

 

关键词: Eye disease;Goodpasture’s syndrome;Laser photocoagulation;Subretinal neovascularisation

 

数据来源: Karger

 

摘要:

Juxtapapillary subretinal neovascular membranes developed in both eyes of a patient who had been treated for Goodpasture’s syndrome for 4 years. These lesions caused visual impairment but were successfully treated by laser photocoagulation. Subretinal neovascularisation has not been reported before in association with Goodpasture’s syndrome, but diverse ocular abnormalities have been described. It is not certain whether these lesions were caused by anti-basement-membrane auto-antibodies. The eyes of 13 other patients with Goodpasture’s syndrome were examined, in order to detect other unsuspected ocular pathology. In 1 further patient, both retinae contained a few unexplained superficial retinal haemorrhages. During follow-up, the original patient developed bilateral peripheral retinoschisis. From this short series and from cases previously described, we conclude that sight-threatening ocular abnormalities are rare in Goodpasture’s syndrome. It is, however, particularly important to be aware of the possibility of treatable eye disease in Goodpasture’s syndrome, since the introduction of effective treatment with immunosuppression and plasmapheresis has made long-term surviv

 

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