Ophthalmic Features of Fourteen Cases of Goodpasture’s Syndrome
作者:
Peter A. Rowe,
David C. Mansfield,
Gordon N. Dutton,
期刊:
Nephron
(Karger Available online 1994)
卷期:
Volume 68,
issue 1
页码: 52-56
ISSN:1660-8151
年代: 1994
DOI:10.1159/000188087
出版商: S. Karger AG
关键词: Eye disease;Goodpasture’s syndrome;Laser photocoagulation;Subretinal neovascularisation
数据来源: Karger
摘要:
Juxtapapillary subretinal neovascular membranes developed in both eyes of a patient who had been treated for Goodpasture’s syndrome for 4 years. These lesions caused visual impairment but were successfully treated by laser photocoagulation. Subretinal neovascularisation has not been reported before in association with Goodpasture’s syndrome, but diverse ocular abnormalities have been described. It is not certain whether these lesions were caused by anti-basement-membrane auto-antibodies. The eyes of 13 other patients with Goodpasture’s syndrome were examined, in order to detect other unsuspected ocular pathology. In 1 further patient, both retinae contained a few unexplained superficial retinal haemorrhages. During follow-up, the original patient developed bilateral peripheral retinoschisis. From this short series and from cases previously described, we conclude that sight-threatening ocular abnormalities are rare in Goodpasture’s syndrome. It is, however, particularly important to be aware of the possibility of treatable eye disease in Goodpasture’s syndrome, since the introduction of effective treatment with immunosuppression and plasmapheresis has made long-term surviv
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