Fine Needle Aspiration Cytodiagnosis As A Pre‐Requisite For Primary Medical Treatment of Breast Cancer
作者:
T. J. POWLES,
P. A. TROTT,
G. CHERRYMAN,
S. CLARKE,
S. ASHLEY,
R. C. COOMBES,
A. L. JONES,
H. D. SINNETT,
A. G. NASH,
期刊:
Cytopathology
(WILEY Available online 1991)
卷期:
Volume 2,
issue 1
页码: 7-12
ISSN:0956-5507
年代: 1991
DOI:10.1111/j.1365-2303.1991.tb00378.x
出版商: Blackwell Publishing Ltd
关键词: breast cancer;breast fine needle aspiration cytodiagnosis;clinical diagnosis;mammographic diagnosis;primary medical treatment;neoadjuvant breast therapy
数据来源: WILEY
摘要:
The accurate non‐surgical diagnosis of breast lumps allows assessment of breast cancer patients for conservation or neoadjuvant primary treatment before surgical intervention. We have analysed the accuracy of clinical assessment, fine needle aspiration cytology (FNAC), and mammography in over 868 women seen in a symptomatic breast clinic. Clinical examination by an experienced breast physician, together with FNAC, detected over 99% of the cancers with a 12% false positive rate. A cytological diagnosis of definite carcinoma was obtained in 69% of women with breast cancer with no false positive result from the women with benign conditions producing a 100% positive predictive value. These results indicate that it would be acceptable to give pre‐surgical systemic endocrine or chemotherapy to women with positive cytology which is therefore a prerequisite for a neoadjuvant therapy progra
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