首页   按字顺浏览 期刊浏览 卷期浏览 Association of paternal alcohol use with gestational age and birth weight
Association of paternal alcohol use with gestational age and birth weight

 

作者: David A. Savitz,   Jun Zhang,   Pamela Schwingl,   Esther M. John,  

 

期刊: Teratology  (WILEY Available online 1992)
卷期: Volume 46, issue 5  

页码: 465-471

 

ISSN:0040-3709

 

年代: 1992

 

DOI:10.1002/tera.1420460511

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractPaternal alcohol use has been associated with a number of adverse reproductive outcomes in laboratory animals and there is one epidemiologic report of a detrimental effect on infant birth weight. To expand the epidemiologic evidence, data from the Child Health and Development Studies were analyzed. Data collected from the onset of prenatal care in 10,232 women enrolled in the Kaiser Foundation Health Plan and residing in the San Francisco East Bay area between June 1959 and September 1966 were available, including information on the mother's report of paternal alcohol consumption and a number of potential confounders. Pregnancy outcomes included preterm delivery (<37 weeks completed gestation), moderately low birth weight (1,501–2,500 g), very low birth weight (≤1,500 g), small‐for‐gestational‐age (<10th percentile of weight for gestational age), and mean birth weight. Paternal alcohol use, analyzed in intervals from 0 to 2.0 or more drinks per day, showed no association with any of the outcomes of interest. Adjusted prevalence odds ratios ranged from 0.7 to 1.5, with no indication of a monotonic dose‐response gradient. Mean birth weight was also virtually unrelated to paternal alcohol use. Compared with the earlier report, this population had a very modest level of alcohol consumption. Nonetheless, within the range that was studied there appears to be no association between paternal alcohol use and birth outcome. © 1992 Wil

 

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