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Dynamics of tropomyosin studied by denaturation of site‐directed mutants

 

作者: C. Ferraz,   G. Trave´,   J. Sri Widada,   F. Heitz,   J. P. Liautard,  

 

期刊: AIP Conference Proceedings  （AIP Available online 1991）
卷期: Volume 226, issue 1  

页码: 326-333

 

ISSN:0094-243X

 

年代: 1991

 

DOI:10.1063/1.40600

 

出版商: AIP

 

数据来源: AIP

 

摘要:

Three mutants of &bgr;‐skeletal tropomyosin were produced by genetic engineering. To test the role of hydrophobic interactions invovled on the dimer formation we performed thermal and urea‐mediated denaturation of these mutants in various solvent conditions. In the light of our results we propose some hypotheses concerning interaction of &agr;‐helices in tropomyosins.

 

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