Low level benzene exposure in sweden: Effect on blood elements and body burden of benzene
作者:
Maths Berlin,
期刊:
American Journal of Industrial Medicine
(WILEY Available online 1985)
卷期:
Volume 7,
issue 5‐6
页码: 365-373
ISSN:0271-3586
年代: 1985
DOI:10.1002/ajim.4700070503
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: blood elements;body burden;chromosome aberrations;low level exposure;personal sampling;toxico‐kinetics
数据来源: WILEY
摘要:
AbstractMeasurements for benzene exposure were performed for different work places. In addition, breath benzene concentrations were measured in different occupations in order to establish toxico‐kinetics of benzene in man; chromosomal aberrations in lymphocytes of exposed workers were also examined. Smoking appears to result in a large increase in benzene concentration in exhaled breath. The smoke from one cigarette contains 60‐80 μg of benzene. It was found that exposure levels of 10 ppm are rather uncommon among workers handling gasoline or gasoline equipment. It was concluded that the gasoline load of road tankers cannot be responsible for chromosome changes of the driver, as milk truck drivers showed the same changes. These results did not prove that benzene was the cause of the observed changes. Smoking is the confounding factor, with a potency of at least the same order of magnitude as benzene. In addition, our present knowledge about mechanisms of benzene is not sufficiently developed to permit quantitative conclusions as to the human health r
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