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Cognitive Recovery in Idiopathic Normal Pressure HydrocephalusA Prospective Study

 

作者: Christian Raftopoulos,   Jeanine Deleval,   Christo Chaskis,   Anne Leonard,   Francis Cantraine,   Frank Desmyttere,   Stephane Clarysse,   Jacques Brotchi,  

 

期刊: Neurosurgery  (OVID Available online 1994)
卷期: Volume 35, issue 3  

页码: 397-405

 

ISSN:0148-396X

 

年代: 1994

 

出版商: OVID

 

关键词: Hydrocephalus;Intracranial pressure;Neuropsychology;Wave analysis

 

数据来源: OVID

 

摘要:

IDIOPATHIC NORMAL-PRESSURE HYDROCEPHALUS remains difficult to treat. Controversy exists as to whether or not shunting can really improve cognitive functions and whether quantified intracranial pressure monitoring (ICP-Mo) can predict postoperative improvement rates. Several studies have drawn attention to the lack of a prospective study concerning the surgical outcome of this condition. We have performed such a study on idiopathic normal-pressure hydrocephalus patients shunted on the basis of ICP-Mo when “high” waves (amplitude >9 mm Hg) were present. Twenty-three patients underwent surgery. The preoperative and postoperative clinical states were assessed by a quantitative procedure blind to the ICP-Mo results. A clear postshunting improvement was seen in 96% of the patients at 1 year with a statistically significant correlation between high wave relative frequency and the grade of improvement (P< 0.05). At the same time, 66.6% of shunted patients showed a significant improvement in cognitive functions. Complications of shunting were successfully managed without residual deficits in this series. We recommend the use of quantitative ICP-Mo as a criterion for surgery and to predict the improvement grade.

 



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