The effect of salicylazosulphapyridine (sulphasalazine) on male fertility. A review
作者:
Aleksander Giwercman,
Niels E. Skakkebæk,
期刊:
International Journal of Andrology
(WILEY Available online 1986)
卷期:
Volume 9,
issue 1
页码: 38-52
ISSN:0105-6263
年代: 1986
DOI:10.1111/j.1365-2605.1986.tb00866.x
出版商: Blackwell Publishing Ltd
关键词: salicylazosulfapyridine;sulphasalazine;male fertility
数据来源: WILEY
摘要:
Salicylazosulfapyridine (SASP), a drug used in the treatment of inflammatory bowel diseases, has been reported to depress the fertility in males.Therefore, some authors have proposed SASP as a new lead in the search for a contraceptive for men. Based on a review of the literature, our conclusion is that SASP taken in tolerable doses has not sufficient antifertility effect. Additionally, the drug has too serious and too many side effects to be accepted as a contraceptive. However, the effect on male fertility of other sulfa drugs and related compounds remains to be investigated.
点击下载:
PDF
(739KB)
返 回