Patients diagnosed with a brain tumor and their families are faced with uncertainties that result from the progression of the disease and treatment regimen. Many strategies can be used to help patients and families deal with these uncertainties. A case report is used to illustrate how changing needs of a patient and family were met by using different strategies.SUMMARYPatient education, support groups, or counseling can help patients and families deal with uncertainty and make informed decisions about treatment modalities. It also promotes the acquisition of a sense of control as an informed consumer of health-care services.Although a support group for people with brain tumors may not be for all patients and families, it can be helpful in dealing with the uncertainties associated with progression of the disease. Structured support groups can be used when the goal is to provide information about brain tumors, whereas an unstructured format can be used to provide a forum for members to vent and deal with their feelings. Members with experience can be instrumental in helping patients and families who are just beginning to deal with the uncertainties with regard to the progression and treatment of brain tumor.