首页   按字顺浏览 期刊浏览 卷期浏览 Long‐Term Outcome of Panic Disorder After Short‐Term Imipramine and Behav...
Long‐Term Outcome of Panic Disorder After Short‐Term Imipramine and Behavioral Group Treatment2.9‐Year Naturalistic Follow‐Up Study

 

作者: LINDA,   NAGY JOHN,   KRYSTAL DENNIS,   CHARNEY KATHLEEN,   MERIKANGAS SCOTT,  

 

期刊: Journal of Clinical Psychopharmacology  (OVID Available online 1993)
卷期: Volume 13, issue 1  

页码: 16-24

 

ISSN:0271-0749

 

年代: 1993

 

出版商: OVID

 

数据来源: OVID

 

摘要:

Twenty-eight patients with a DSM-III diagnosis of agoraphobia with panic attacks who completed a 4-month combined drug and behavioral treatment program and who were then discharged on imipramine were interviewed 1 to 5 years after being discharged. At the time of follow-up, half of the patients were medication free, eight were receiving a lower dose of imipramine, two were receiving the same dose as at the time of discharge, and four patients were receiving other antipanic medications. Panic attack frequency remained reduced at the time of follow-up, as did all anxiety and all impairment ratings. These improvements were similar between patients receiving and not receiving imipramine at this time. Long-term outcome was independent of nonphar-macological therapy during the follow-up interval and lifetime diagnosis of major depression at the time of admission. Our data suggest that improvement observed after 4 months of treatment with imipramine and behavioral therapy is maintained after 1 to 5 years, even for many patients who reduced the dose of or discontinued imipramine. Long-term, randomized studies are needed to compare the efficacy of treatments and to determine treatment duration.

 

点击下载:  PDF (918KB)



返 回