Adverse Infant Outcomes Associated With First-Trimester Vaginal Bleeding
作者:
MICHELLE WILLIAMS,
ROBERT MITTENDORF,
ELLICE LIEBERMAN,
RICHARD MONSON,
期刊:
Obstetrics & Gynecology
(OVID Available online 1991)
卷期:
Volume 78,
issue 1
页码: 14-18
ISSN:0029-7844
年代: 1991
出版商: OVID
数据来源: OVID
摘要:
We assessed the association between first-trimester vaginal bleeding and singleton infant outcomes in a hospital-based population of 11,444 nondiabetic women. Low birth weight (LBW), shortened gestation, LBW at term, and neonatal death occurred more often in women reporting first-trimester bleeding than in those who never bled. These relationships remained statistically significant after adjusting for confounding factors. Women who experienced vaginal bleeding limited to the first trimester (N=1174) had double the risk of delivering a preterm infant compared with those experiencing no bleeding (adjusted risk ratio=2.0; 95% confidence interval 1.6-2.5). Bleeding limited to the first trimester was associated with a 1.6-fold risk of delivery of a term LBW infant (95% confidence interval 1.3-2.0). These results suggest that first-trimester vaginal bleeding is an important correlate of adverse infant outcomes.
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