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Do Amino Acids Reverse the Sickling of Erythrocytes Containing Hemoglobin S?

 

作者: ShirahamaKeishiro,   KubotaShigeo,   YangJen Tsi,  

 

期刊: Hemoglobin  （Taylor Available online 1980）
卷期: Volume 4, issue 2  

页码: 149-155

 

ISSN:0363-0269

 

年代: 1980

 

DOI:10.3109/03630268009042381

 

出版商: Taylor&Francis

 

数据来源: Taylor

 

摘要:

Homoserine, asparagine and glutamine do not restore the de-formability of deoxygenated sickle cells in spite of noticeable morphological changes. These amino acids also do not raise the minimum gelling concentration of deoxyhemoglobin S. The use of these compounds as anti-sickling agents is therefore doubtful.

 

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