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Nephrotic-Range Proteinuria in a Patient with High Renin Hypertension: Effect of Treatment with an ACE-lnhibitor

 

作者: Dino Docci,   Giovanni Moscatelli,   Claudio Capponcini,   Leopoldo Baldrati,   Carlo Feletti,  

 

期刊: American Journal of Nephrology  （Karger Available online 1992）
卷期: Volume 12, issue 5  

页码: 387-389

 

ISSN:0250-8095

 

年代: 1992

 

DOI:10.1159/000168479

 

出版商: S. Karger AG

 

关键词: Proteinuria;Hypertension;Renin-angiotensin system;ACE-inhibition

 

数据来源: Karger

 

摘要:

A 65-year-old man presented proteinuria in the nephrotic range that occurs in the setting ofhigh renin hypertension. Proteinuria persisted after normalizing blood pressure by nifedipine. In contrast, treatment with an ACE-inhibitor (enalapril) resulted in the prompt resolution of the proteinuria. Interestingly, proteinuria relapsed after removing the ACE-inhibition. These observations suggest a causal relation between the overactivity of the renin-angiotensin system in this patient and his proteinuria.

 

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