Increased Cerebral Blood Flow After Brain Arteriovenous Malformation Resection Is Substantially Independent of Changes in Cardiac Output
作者:
Tomoki Hashimoto,
William Young,
Isak Prohovnik,
Dhanesh Gupta,
Noeleen Ostapkovich,
Eugene Ornstein,
Alexander Halim,
Christopher Quick,
期刊:
Journal of Neurosurgical Anesthesiology
(OVID Available online 2002)
卷期:
Volume 14,
issue 3
页码: 204-208
ISSN:0898-4921
年代: 2002
出版商: OVID
关键词: Arteriovenous malformations;Cerebral blood flow;Cardiac output;Hyperperfusion
数据来源: OVID
摘要:
Brain arteriovenous malformation (BAVM) resection can result in an acute increase in cerebral blood flow (CBF) of unclear etiology. This observational study investigated the relationship between changes in CBF and cardiac output (CO) in patients undergoing microsurgical resection of BAVMs. In 20 patients undergoing a BAVM resection during an isoflurane-based anesthesia, we measured CBF and systemic cardiovascular parameters immediately before and after BAVM resection. CBF was measured on the hemisphere ipsilateral to the lesions and on the contralateral side, using intravenous cold133Xe washout. Cardiac output was measured using thermodilution technique via a pulmonary artery catheter. There was an increase in global CBF after resection (25 ± 8 versus 31 ± 13 mL/100 g/min, preresection versus postresection, mean ± SD,P= .002), ipsilateral CBF (25 ± 8 versus 31 ± 13 mL/100 g/min,P= .002), and contralateral CBF (24 ± 7 versus 30 ± 13 mL/100 g/min,P= .003). There was no change in CO, mean systemic arterial pressure, central venous pressure, or pulmonary artery diastolic pressure. The change in CBFGLOBALwas not correlated with changes in CO (r= .154,P= .517). BAVM resection resulted in global increases in CBF that was not substantially related to changes in CO or other systemic parameters.
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