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Synthesis Of N,N‐dimethyl‐[β‐(3,4‐diacetoxy‐6‐123I‐iodophenyl)]‐ethylamine (IDDE): A potential radiotracer for the study of the dopaminergic system

 

作者: Michael J. Adam,   Yolanda Zea Ponce,   Joffre M. Berry,   Jianming Lu,  

 

期刊: Journal of Labelled Compounds and Radiopharmaceuticals  （WILEY Available online 1992）
卷期: Volume 31, issue 1  

页码: 3-10

 

ISSN:0362-4803

 

年代: 1992

 

DOI:10.1002/jlcr.2580310103

 

出版商: John Wiley&Sons, Ltd.

 

关键词: [123I];dopamine metabolism;SPECT;MAO

 

数据来源: WILEY

 

摘要:

AbstractN.N‐Dimethyl‐[β‐(3,4‐Diacetoxy‐6‐123I‐Iodophenyl)]ethylamine (IDDE) was synthesized by the iododemercuration reaction with [123I]‐NaI and Chloramine‐T. The iodinated compound was deprotected with BBr3, acetylated and purified by HPLC to give the final product in 43% radiochemical yield. The radiochemi

 

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