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Pre-Incubation and Low Temperatures in Quantitative Radioreceptor Assays

 

作者: K. Ensing,   R.A. De Zeeuw,  

 

期刊: Analytical Letters  （Taylor Available online 1984）
卷期: Volume 17, issue 14  

页码: 1647-1658

 

ISSN:0003-2719

 

年代: 1984

 

DOI:10.1080/00032718408065338

 

出版商: Taylor & Francis Group

 

关键词: Radioreceptor assay;Temperature;pre-incubation anticholinergic

 

数据来源: Taylor

 

摘要:

The detection limits of drugs in quantitative RRA are primarily determined by their affinities towards the receptor. Yet, the concentration of radiolabeled ligand, necessary for quantification of receptor-bound drug, increases the theoretical detection limit. Therefore the influences of low temperatures and pre-incubation on the detection limit was studied.

 

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