CONCENTRATION OF GUANIDINES IN NORMAL HUMAN PLASMA
作者:
I. Lazdins,
J. K. Dawborn,
期刊:
Clinical and Experimental Pharmacology and Physiology
(WILEY Available online 1978)
卷期:
Volume 5,
issue 1
页码: 75-80
ISSN:0305-1870
年代: 1978
DOI:10.1111/j.1440-1681.1978.tb00654.x
出版商: Blackwell Publishing Ltd
关键词: guanidines;guanidinosuccinic acid;methylguanidine;uraemi.
数据来源: WILEY
摘要:
SUMMARY1. The concentration of methylguanidine and guanidinosuccinic acid has been measured in normal human plasma and discrepancies between various published methods for measuring methylguanidine have been resolved. Previous methods have been modified to allow these guanidines, together with guanidinoacetic acid and creatine, to be measured on the same serum sample.2. Mean values in six normal subjects were as follows: methylguanidine 1.62 μmol/1 (s.d. = 1.3); guanidinosuccinic acid 0.66 μmol/1 (s.d. = 0.22); guanidinoacetic acid 7.06μmol/l (s.d. = 1.29); creatine 80.9μmol/l (s.d. = 37
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