Effect of Intra‐arterial Insulin on Tissue Cholesterol and Fatty Acids in Alloxan‐Diabetic Dogs
作者:
Anatolio,
Cruz Donald,
Amatuzio Francisco,
Grande Lyle,
期刊:
Circulation Research
(OVID Available online 1961)
卷期:
Volume 9,
issue 1
页码: 39-43
ISSN:0009-7330
年代: 1961
出版商: OVID
数据来源: OVID
摘要:
Insulin and saline were injected into the right and left femoral arteries respectively of 19 alloxan-diabetes-mellitus dogs for 1 to 28 weeks. A significant increase of artery tissue cholesterol and total fatty acids was found on comparing the insulin-administered right leg with the saline-administered left leg. Similarly, a significant increase of total fatty acids in muscle was found on comparing the right with the left leg of the alloxan-diabetes mellitus dogs. No significant differences were observed in the normal animals when the insulin-injected side was compared with the noninjected.
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