The gold mineralization at the Rodalquilar mine in southern Spain is of the acid-sulphate type. We have assessed the ability of AVIRIS imaging spectrometer data to detect the hydrothermal alteration mineralogy mapped using traditional ground-based techniques at Rodalquilar. Four methods of retrieving apparent surface reflectance have been evaluated, the empirical line method and three methods of radiative transfer modelling. This study indicates that radiative transfer modelling, using only atmospheric information derived from the imaging spectrometry data, can satisfactorily correct the atmospheric effects involved in retrieving apparent surface reflectance. The alteration at Rodalquilar is characterized by propylitic (vermiculite), illitic, kaolinitic (pyrophyllitic), alunitic and silicic zones with an increasing degree of alteration towards the formative hydrothermal cells in whose fossil cores the gold mineralization is found. However, several factors act against the usefulness of the AVIRIS data for mapping these mineral zones: the mine site is heavily disturbed with exposed workings, often of high albedo altered rocks, whilst unworked areas have partial iron-rich soil and dry vegetation cover; the alteration itself is highly discontinuous at the scale of 10 m and the shortwave infrared (SWIR) data where much of the diagnostic information for these hydrothermal minerals lies is very noisy. Nevertheless it has proved possible to map successfully, at the individual pixel level, the zones of gold-bearing alunitic alteration using the joint presence of alunite absorption features at 1480 and 1760 nm. The data from the 2000-2400 nm spectral range allow the areas with general absorption features centred around 2200 nm to be mapped but zonation based on individual minerals identification is not possible.