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Assessment of Sudomotor Dysfunction in Early Parkinson’s Disease

 

作者: Mikihiro Kihara,   Yoriko Kihara,   Tadashi Tukamoto,   Yoshiko Nishimura,   Haruo Watanabe,   Ryouichi Hanakago,   Akira Takahashi,  

 

期刊: European Neurology  （Karger Available online 1993）
卷期: Volume 33, issue 5  

页码: 363-365

 

ISSN:0014-3022

 

年代: 1993

 

DOI:10.1159/000116972

 

出版商: S. Karger AG

 

关键词: Sudomotor dysfunction;Parkinson’s disease;Sympathetic response;Thermal warming;Thyrotropin-releasing hormone

 

数据来源: Karger

 

摘要:

We performed a quantitative sudomotor function test on 10 patients with early Parkinson’s disease (PD) and 11 age-matched control subjects. Thermal warming increased the sweat rate in both PD and controls. There was no difference in sweat rate between the forearm and the thigh in either PD or controls. In PD, thyrotropin-releasing hormone (TRH) did not increase the sweat rate, whereas it did so in the controls. These results suggest that sudomotor dysfunction in early PD is minor but that there may be an impairment of TRH-induced sympathetic response in the early stages of P

 

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