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Nisoldipine: A New Dihydropyridine Calcium‐Channel Blocker

 

作者: Judith Mitchell,   William Frishman,   Mark Heiman,  

 

期刊: The Journal of Clinical Pharmacology  (WILEY Available online 1993)
卷期: Volume 33, issue 1  

页码: 46-52

 

ISSN:0091-2700

 

年代: 1993

 

DOI:10.1002/j.1552-4604.1993.tb03902.x

 

出版商: Blackwell Publishing Ltd

 

数据来源: WILEY

 

摘要:

Nisoldipine is a new calcium‐channel blocker of the dihydropyridine subclass, with a chemical structure similar to nifedipine. It has been used in clinical trials to assess its efficacy and safety in patients with hypertension, angina pectoris, and congestive heart failure. Similar to other dihydropyridines, nisoldipine is a potent peripheral and coronary dilator. The most optimal dosage regimen has not been established in clinical trials. The drug appears to have a favorable side‐effect prof

 

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